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纪雪亮,王 意,蓝 蔚,刘衍智,易先锋.压力治疗对烧伤后增生性瘢痕的远期影响[J].中国康复医学杂志,2016,(5):521~525
压力治疗对烧伤后增生性瘢痕的远期影响    点此下载全文
纪雪亮  王 意  蓝 蔚  刘衍智  易先锋
广东省工伤康复医院烧伤整形及烧伤康复科,广州,510440
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摘要:
      摘要 目的: 研究长期的压力治疗对增生性瘢痕的影响。 方法: 选取2012年入住我院的深度烧伤后增生性瘢痕30例患者作为试验组,以压力衣或弹力绷带进行压力治疗,直至瘢痕成熟后2个月或试验持续24个月。在同期的门诊患者中,选取30例因各种原因无法进行压力治疗的深度烧伤后增生性瘢痕患者作为对照组。观察2组患者增生性瘢痕生长过程中,瘢痕生长速度(厚度)、羟脯氨酸、组胺、5-羟色胺等指标的表达差异。 结果:①试验组瘢痕较对照组薄且生长周期相对较短,差异有显著性意义。②试验组患者的羟脯氨酸浓度水平低于对照组且降低的时间较早,差异有显著性意义。③组胺、5-羟色胺的浓度变化与瘢痕生长的相关程度不明显,差异无显著性意义。 结论:压力治疗对增生性瘢痕有抑制的效果,长期坚持可促进增生性瘢痕的提前成熟。建议压力治疗应贯穿于瘢痕的整个生长过程。
关键词:压力治疗  烧伤  瘢痕  远期影响
A study on long-term effects of pressure therapy on hypertrophic scar after burns    Download Fulltext
Dept. of Burns and Plastic Surgery and Burn Rehabilitation, Guangdong Provincial Work Injury Rehabilitation Hospital, Guangzhou,510440
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Abstract:
      Abstract Objective:To study the long-term effects of pressure therapy on hypertrophic scar after burns. Method:In 2012 30 inpatients who meet the criteria for inclusion were selected. These patients had hypertrophic scar after burns. Then,pressure therapy were carried out for them until the scar were ripe for 2 month or the experiment lasted for 24 months. These patients were compared with a control group of 30 outpatient.The thickness of scar,hydroxyproline,histamine,and 5-hydroxytryptamine of these patients of 2 groups were tested. Result:①The thickness of scar in experimental group were thinner than those in control group. And it's growth cycle were shorter. ②The hydroxyproline concentration level of experimental group were lower than those in control group, and reduced early. ③The degrees of correlation with changes in concentrations of histamine, 5- hydroxytryptamine were not obvious with scar growth. Conclusion:Pressure therapy had inhibitory effects on hypertrophic scar. And long-term adherence could promote the hypertrophic scar maturation. So the pressure therapy should persevere in the whole growth process of hypertrophic scar.
Keywords:pressure therapy  burn  scar  long-term effect
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