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彭争荣,王素娥,袁 静,肖平田.高压氧对脑外伤患者精神障碍的影响[J].中国康复医学杂志,2008,23(8):715~717
高压氧对脑外伤患者精神障碍的影响    点此下载全文
彭争荣  王素娥  袁 静  肖平田
中南大学湘雅医院高压氧科,长沙,410008
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DOI:
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摘要:
      目的:评价高压氧(HBO)治疗脑外伤(TBI)的效果,探讨HBO治疗TBI精神障碍的临床价值。方法:将60例脑外伤患者分为高压氧综合治疗组和对照组,两组均以格拉斯哥结局量表(GOS)判断疗效,并测定两组患者治疗前后MQ、HDS、HAMD得分,进行比较判定。结果:高压氧组治疗后GOS评分为4.37±0.96,对照组为3.77±0.97,高压氧组明显优于对照组,差异具有显著性(P<0.05)。两组患者治疗前MQ、HDS得分明显减少,治疗后均较治疗前增加,差异具有显著性(P<0.01),高压氧组MQ、HDS得分明显高于对照组,差异具有显著性(P<0.05)。两组患者治疗前HAMD得分明显提高,治疗后均较治疗前降低,HBO组HAMD得分明显低于对照组,差异具有显著性(P<0.05)。结论:HBO能进一步提高TBI患者MQ、HDS得分,降低TBI患者HAMD得分,促进患者脑功能的恢复,增加治疗疗效,改善TBI患者精神心理状态。
关键词:高压氧;脑外伤;长谷川痴呆量表  记忆商数  汉密尔顿抑郁量表
Influence of hyperbaric oxygen on mental disorders in patients with traumatic brain injury    Download Fulltext
Department of Hyperbaric Oxygen, Xiangya Hospital, Central South University, Changsha 410008, China
Fund Project:
Abstract:
      Objective: To evaluate the effects of hyperbaric oxygen(HBO) therapy on mental disorders of patients with traumatic brain injury(TBI). Method: Sixty patients with TBI were divided into two groups randomly: HBO (combined treatment) group and control group. The curative effects of HBO group and control group were measured after 3 courses of treatment by means of Glasgow outcome scale(GOS). The scores of MQ、HDS and HAMD in both groups were measured before and after 3 courses of treatment. Result: The GOS scores of HBO group was 4.37±0.96, that of control group was 3.77±0.97, HBO group had a preferable effect(P<0.05). After 3 courses of treatment, the scores of MQ, HDS elevated in both groups(P<0.01), and in HBO group that was obvious higher than that in control group(P<0.05); while the scores of HAMD redueed in both groups, and there was significant difference between two groups(P<0.05), that in HBO group was obvious lower than that in control group. Conclusion: ①The therapeutic effect of HBO combined with conventional neurosurgery therapy is much better than that of conventional neurosurgery therapy only. ②HBO can elevate the scores of MQ、HDS and reduce the scores of HAMD in patients with TBI, accordingly HBO can improve mental state in patients with TBI.
Keywords:hyperbaric oxygen  traumatic brain injury  memory quotient  Hastgawa dementia scale  Hamilton depression rating scale
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